Impact of Steroid, Diuretic, and Fluid Use on BPD Outcomes

Purpose

Assess the impact of steroid, diuretic, and fluid practices on BPD outcomes in extreme premature infants in the Banner - University Medical Center Phoenix (BUMCP) neonatal intensive care unit (NICU).

Condition

  • BPD - Bronchopulmonary Dysplasia

Eligibility

Eligible Ages
All ages
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Infants born at <30 weeks and/or <1500g - Admitted to BUMCP between January 1, 2019 and December 31, 2020

Exclusion Criteria

  • Infants that do not survive to 36 weeks CGA, when the determination of BPD is made - Infants that are transferred to another hospital prior to 36 weeks CGA - Out born infants - Infants with life threatening congenital anomalies - Investigator discretion as to other factors which might impact the study

Study Design

Phase
Study Type
Observational
Observational Model
Case-Only
Time Perspective
Retrospective

Arm Groups

ArmDescriptionAssigned Intervention
Inclusion Group Infants born at <30 weeks and/or <1500g that were admitted to BUMCP between January 1, 2019 and December 31, 2020
  • Other: No interventions or procedures
    This is a retrospective observational study and data will be collected from the subject's existing medical record. No interventions or procedures will be required for this study.

More Details

Status
Active, not recruiting
Sponsor
Pediatrix

Study Contact

Detailed Description

The investigators propose performing a retrospective analysis of the current respiratory management methods to potentially find a correlation between the number of steroid doses administered, the timing of initiation of steroid therapy and the effect on premature infants at risk for developing BPD. The investigators are also going to explore the number and timing of diuretic medications and average fluid intake.